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Karolinska Institutet
Stockholm Nobel Institute for Neurophysiology
Department of Neuroscience

17177 - Stockholm

+46 8 5248 7345
+46 8 349 544


Job opportunities

Dr Gilad Silberberg
Microcircuits in the basal ganglia and neocortex
The European Neuroscience Institute at Karolinska Institutet, Stockholm

Research Area

Our primary interest is to understand sensory-motor processes, by studying the structure and dynamics of the underlying neuronal microcircuits.
The regions of interest are the neocortex and basal ganglia, and the synaptic connections between these brain areas.
The techniques used include whole-cell recordings from neurons in vitro and in vivo, dendritic patch-recordings, 3D morphological reconstructions of recorded neurons, as well as computational modeling.


Selected Publications:

Richardson, M.J. & G. Silberberg, Measurement and analysis of postsynaptic potentials using a novel voltage-deconvolution method. J Neurophysiol, 2008. 99(2): p. 1020-31.

Silberberg, G., Polysynaptic subcircuits in the neocortex: spatial and temporal diversity. Curr Opin Neurobiol, 2008. 18(3): p. 332-7.

Silberberg, G. & H. Markram, Disynaptic Inhibition between Neocortical Pyramidal Cells Mediated by Martinotti Cells. Neuron, 2007. 53(5): p. 735-46.

Silberberg, G., S. Grillner, F.E. Lebeau, R. Maex & H. Markram, Synaptic pathways in neural microcircuits. Trends Neurosci, 2005. 28(10): p. 541-51.

Kalisman*, N., G. Silberberg* & H. Markram, The neocortical microcircuit as a tabula rasa. Proceedings of the National Academy of Sciences of the United States of America, 2005. 102(3): p. 880-885.

Silberberg, G., C.Z. Wu & H. Markram, Synaptic dynamics control the timing of neuronal excitation in the activated neocortical microcircuit. Journal of Physiology-London, 2004. 556(1): p. 19-27.

Silberberg, G., M. Bethge, H. Markram, K. Pawelzik & M. Tsodyks, Dynamics of population rate codes in ensembles of neocortical neurons. Journal of Neurophysiology, 2004. 91(2): p. 704-709.

Technical Expertise