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Institute of Reconstructive Neurobiology
University Bonn / LIFE & BRAIN Center
Sigmund-Freud-Str. 25

53127 - Bonn

+49 228-6885-541
+49 228-6885-501

Job opportunities

Prof Harald Neumann
Neuroimmunology, Neural Regeneration
European Neuroscience Institute, Göttingen

Research Area

The major objective of our research is to understand the involvement of inflammation in neuronal injury as well as neuronal protection and regeneration. Furthermore, adult hematopoietic-derived stem and precursor cells will be applied as tool for cell and gene therapy of neuroinflammatory and neurodegenerative diseases.

more information:


Stagi M., Dittrich P., Frank N., Iliev A., Schwille P and Neumann H.(2005):Breakdown of axonal synaptic vesicle precursor transport by microglial nitric oxide..J. Neurosci., 25(2):352-62

Takahashi K., Rochford C.D. and Neumann H.(2005):Clearance of apoptotic neurons without inflammation by microglial triggering receptor expressed on myeloid cells-2..J. Exp. Med., 201(4):647-57

Liu Y., Walter S., Stagi M., Cherny D., Letiembre M., Schulz-Schaeffer W., Heine H., Penke B., Neumann H. and Fassbender K.(2005):LPS receptor (CD14): a receptor for phagocytosis of Alzheimer’s amyloid peptide..Brain, 128(Pt 8):1778-89

Iliev, A., Stringaris, A.K., Nau, R. and Neumann,H.(2004):Neuronal injury mediated via stimulation of microglial toll-like receptor-9 (TLR9)..FASEB J. 18, 412-414:1091-100

Kempermann. G., Neumann, H.(2003):Microglia: The enemy within?..Science 302, 1689-1690 (Perspective):
Neumann H.(2003):Molecular mechanisms of axonal damage in inflammatory central nervous system diseases..Curr. Opin. Neurology, 16:267-273 (Review)

KempermaaNeumann H., Medana I., Bauer J., Lassmann H.nn. G., Neumann, H.(2002):Cytotoxic T lymphocytes in autoimmune and degenerative CNS diseases..Trends in Neurosci. 25 (6), 313-319 (Review):

Neumann,H., Schweigreiter,R., Yamashita,T., Rosenkranz,K., Wekerle,H. and Barde,Y.-A.(2002):Tumor necrosis factor inhibits neurite outgrowth and branching of hippocampal neurons by a Rho-dependent mechanism..Trends iJ. Neurosci. 22:854-862

Neumann,H.(2001):Control of glial immune function by neurons..Glia, 36:191-199 (Review)

Medana,I., Li,Z., Flügel,A., Tschopp,J., Wekerle,H., and Neumann,H.(2001):Fas Ligand (CD95L) protects neurons against perforin-mediated T lymphocyte cytotoxicity..J. Immunol. 167:674-681

Medana,I., Martinic, M.M.A., Wekerle,H. and Neumann,H.(2001):Transection of major histocompatibiltiy class I-induced neurites by cytotoxic T lymphocytes..Am. J. Pathol. 159:809-815


Technical Expertise