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Max-Planck-Institute for Experimental Medicine
Hermann-Rein-Str. 3

37075 - Göttingen

+49 551 3899 646
+49 551 3899 644

Job opportunities

Prof Walter Stühmer
Molecular Biology of Neuronal Signals
European Neuroscience Institute, Göttingen

Research Area

Investigations on structure-function relationships of native and genetically modified ion channels, on origin and distribution as well as on genetic and physiological regulation of expression of different ion channels and membrane proteins are accomplished by in situ and in vitro methods. By combination of TIRFM (Total Internal Reflection Fluorescence Microscopy) with FRET (Fluorescence Resonance Energy Transfer) methods protein interactions at cell membranes are studied. In the focus of the research team is the analysis of physiological functions of ion channels during neuronal interactions and development and during cancerogenesis.


Technical Expertise
  • Martin S, Lino de Oliveira C, Mello de Queiroz F, Pardo LA, Stühmer W, and Del Bel E (2008) Eag1 potassium channel immunohistochemistry in the CNS of adult rat and selected regions of human brain. Neuroscience 155, 833-844

  • Downie BR, Sánchez A, Knötgen H, Contreras-Jurado C, Gymnopoulos M, Weber C, Stühmer W, and Pardo LA (2008) Eag1 expression interferes with hypoxia homeostasis and induces angiogenesis in tumors. J. Biol. Chem. 283, 36234-36240

  • Alves F, Dullin C, Napp J, Missbach-Guentner J, Jannasch K, Mathejczyk J, Pardo LA, Stühmer W, and Tietze L-F (2009) Concept of a selective tumour therapy and its evaluation by near-infrared flurorescence imaging and flat-panel volume computed tomography in mice. Eur. J. Radiology 70, 286-293

  • Gómez-Varela, D., Kohl, T., Schmidt, M., Rubio, M.E., Kawabe, H., Nehring, R., Schäfer, S., Stühmer, W. and Pardo, L. (2010) Characterization of Eag1 channel lateral mobility in rat hippocampal cultures by single-particle-tracking with quantum dots. PLoS ONE 5, e8858

  • Gonçalves, J.T. and Stühmer, W. (2010) Calmodulin interaction with hEAG1 visualized by FRET microscopy. PLoS ONE 5(5): e10873