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Centre for Neuroregeneration
University of Edinburgh
Chancellor´s building
49 Little France Crescent
EH16 4SB - Edinburgh
UK

+44 (0) 131 242 7986
+44 (0) 131 242 7978


Job opportunities

Dr David Lyons
Neuroscience
Centre for Neuroregeneration University of Edinburgh

Research Area

Publications

Almeida RG, Czopka, T, ffrench-Constant C, and Lyons DA
Individual axons regulate the myelinating potential of single oligodendrocytes in vivo
Development (2011) 138: 4443-4450

Czopka T and Lyons DA.
Dissecting mechanisms of myelinated axon formation using zebrafish.
Methods in Cell Biology (2011) 105: 25-62.

Raphael AR, Lyons DA, and Talbot WS
ErbB signaling has a role in radial sorting independent of Schwann cell number.
Glia (2011) 59: 1047-55

Lyons DA, Naylor SG, Scholze, and Talbot WS.
Kif1b is essential for mRNA localization in oligodendrocytes and development of myelinated axons.
Nature Genetics (2009) 41: 854-858.

Lyons DA, Naylor SG, Mercurio S, Dominguez C, and Talbot WS.
KBP is essential for axonal structure, outgrowth, and maintenance in zebrafish, providing insight into the cellular basis of Goldberg-Shprintzen syndrome
Development (2008) 135: 599-608

Tawk M, Araya C, Lyons DA, Reugels AM, Girdler GC, Bayley PR, Hyde DR, Tada M and Clarke JD.
A mirror-symmetric cell division that orchestrates neuroepithelial morphogenesis.
Nature (2007) 446: 797-800

Voas MG, Lyons DA, Naylor SG, Arana N, Rasband MN and Talbot WS.
alphaII-Spectrin Is Essential for Assembly of the Nodes of Ranvier in Myelinated Axons.
Current Biology (2007) 17: 562-8.

Pogoda HM, Sternheim N, Lyons DA, Diamond B, Hawkins TA, Woods IG, Bhatt DH, Franzini-Armstrong C, Dominguez C, Arana N, Jacobs J, Nix R, Fetcho JR,and Talbot WS.
A genetic screen identifies genes essential for development of myelinated axons in zebrafish.
Developmental Biology (2006) 298(1):118-31.

Woods IG, Lyons DA, Voas MG, Pogoda HM and Talbot WS.
nsf is essential for organization of myelinated axons in zebrafish.
Current Biology (2006) 16: 636-48.

Lyons DA, Pogoda HM, Voas MG, Woods IG, Diamond B, Nix R, Arana N, Jacobs J, and Talbot WS.
erbb3 and erbb2 are essential for Schwann cell migration and myelination in zebrafish.
Current Biology (2005) 15: 513-524.

Lyons DA, Guy AT and Clarke JDW.
Monitoring neural progenitor fate through multiple rounds of division in an intact vertebrate brain.
Development (2003) 130: 3427-3436.


Reviews

Lyons DA and Talbot WS.
Axonal domains: role for paranodal junction in node of Ranvier assembly.
Current Biology (2008) 18:R876-9.

Community resource

Rauch, GJ, Lyons, DA, Middendorf I, Friedlander B, Arana, N, Reyes, T. and Talbot, WS.
Submission and Curation of Gene Expression Data
ZFIN Direct Data Submission (http://zfin.org).


Technical Expertise

·      Zebrafish genetics and chemical biology

·      Live cell in vivo imaging

·      Developmental neurobiology