Our group focuses its research on three main areas:

1. Study of genetic factors involved in the pathogenesis of Parkinson´s disease (PD) and other movement disorders.In the last few years numerous genes related to the pathophysiology of movement disorders have been described. Our group is interested in the characterisation of these genes, as well as of other possible candidate genes. Our final objective is to investigate the functional consequences of the alterations of these genes in our population by means of the phenotype-genotype correlation analysis and studies of genetic linkage.

2. Transcraneal magnetic stimulation (TMS) in the study of the pathophysiology of PD and other movement disorders.In this line our group attempts to evaluate, using TMS, the role of various areas of the brain in the pathophysiology of PD and other movement disorders, as well as their modulation by drugs, functional surgery and genetic factors.

3. Studies of the clinical aspects of PD and other movement disorders.The objective of this line is focussed on the more clinical aspects of movement disorders, describing unusual presentations of different diseases and differential clinical characteristics of some entities. The study of the efficacy of various therapies is also included, as well as the diagnostic value of different neuroimaging tests in PD and other movement disorders.

For further information, please also see: http://www.ibis-sevilla.es/investigaci%C3%B3n/neurociencias/trastornos-del-movimiento/mir-rivera,-pablo.aspx

5 Selected Publications

Carrillo F., Palomar FJ., Conde V., Diaz-Corrales FJ., Porcacchia P., Fernández-Del-Olmo M., Koch G., Mir P. (2013) Study of cerebello-thalamocortical pathway by transcranial magnetic stimulation in Parkinson´s disease. Brain Stimul., 6 (4) : 582-9.

Palomar FJ., Conde V., Carrillo F., Fernández-del-Olmo M., Koch G., Mir P. (2013) Parieto-motor functional connectivity is impaired in Parkinson’s disease. Brain Stimul., 6 (2) : 147-54.

Palomar FJ., Suárez A., Franco E., Carrillo F., Gil-Néciga E., Mir P. (2013) Abnormal sensorimotor plasticity in CADASIL correlates with neuropsychological impairment. J. Neurol. Neurosurg. Psychiatry, 84 (3) : 329-36.

Benítez-Rivero S., Marín-Oyaga VA., García-Solís D., Huertas-Fernández I., García-Gómez FJ., Jesús S., Cáceres MT., Carrillo F., Ortiz AM., Carballo M., Mir P. (2013) Clinical features and 123I-FP-CIT SPECT imaging in vascular parkinsonism and Parkinson´s disease. J. Neurol. Neurosurg. Psychiatry, 84 (2) : 122-9.

Palomar F.J, Díaz-Corrales F., Carrillo F., Fernández del Olmo M., Koch G., Mir P. (2011) Sensory perception changes induced by transcranial magnetic stimulation over the primary somatosensory cortex in Parkinson´s disease. Mov. Disord., 26 (11) : 2058-64.

Awards, Fellowships and Honours

2009            Prize for the Best Young Investigator in Biomedicine in Andalusia

• Parkinson Disease
• Dystonia
• Movement Disorders
• Neural Plasticity
• Transcranial Magnetic Stimulation
• Neurogenetics